Optimization, Endophyte Lansano bacteria [Pterocarpus indicus Willd], BA 1 isolate, Antibiotic

Increasing cases of antibiotic resistance encourage researchers to find new bioactive compounds. The source of the newly developed antibiotics is utilizing endophytic bacteria. BA1 isolate is an endophytic bacterium from Lansano plant (Pterocarpus indicus Willd) which has high antimicrobial activity. Antibiotic compounds are produced through a fermentation process. The purpose of this study was to optimize the fermentation conditions of endophytic bacteria Lansano isolate BA1 in producing antibiotic compounds. Optimization of the fermentation time was carried out for 72 hours.